Calreticulin Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA1903 | 100 µL | 620,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-903 detects calreticulin from human, rat, mouse, hamster, rabbit and canine tissues. PA1-903 has been successfully used in Western blot, immunoprecipitation, immunocytochemistry and immunofluorescence procedures. By Western blot, this antibody detects an ~60 kDa protein representing calreticulin and an ~120 kDa unidentified protein from rat brain extract. PA1-903 immunizing peptide corresponds to amino acid residues 399-414 from mouse calreticulin. PA1-903 immunizing peptide (Cat. # PEP-017) is available for use in neutralization and control experiments. Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
Category | Antibody |
Supplier | ThermoFisher |
Application | ICC, IP, WB |
Regulatory Status | RUO |
Immunogen | Synthetic Peptide: D(399) E K E E D E E E S P G Q A K D(414). |
Host | Ck |
Genebank | CALR |
Isotype | IgY |
Crossreactivity | Dg, Hm, Hu, Ms, Rb, Rt |
Clonality | Pab |
Format | Liquid; , with 1mg/mL BSA and 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Western Blot (1:2,000), Immunocytochemistry (Assay-dependent), Immunoprecipitation (Assay-dependent) |
Purity | Antigen affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: PA1-903 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |