NBS1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA316528 | 50 µL | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
ICC/IF has been performed using methanol-fixed IMR90 primary human fibroblasts. Suggested positive control: antigen standard for NBN (transient overexpression lysate), TK6 and HeLa whole cell extract. The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Partial length human NBS1 protein [Swiss-Prot #O60934] |
| Host | Rb |
| Genebank | NBN |
| Isotype | IgG |
| Crossreactivity | Hm, Hu, Ma, Ms, Primate |
| Clonality | Pab |
| Format | Liquid; whole serum; , with 0.02% sodium azide |
| Working Dilution | Immunoprecipitation (3 µL), Flow Cytometry (Assay-Dependent), Immunocytochemistry (1:50-1:200), C... |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: PA3-16528 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
