SR-BI Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA316786 | 100 µL | 674,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: mouse liver lysate or protein. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, N, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A peptide containing residues 496-509 from mouse SR-BI plus an N-terminal cysteine was coupled to KLH. CSPAAKGTVLQEAKL-COOH. |
| Host | Rb |
| Genebank | SCARB1 |
| Isotype | IgG |
| Crossreactivity | Bo, Hm, Hu, Ms, Mustelid, Primate, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (1:400), Immunoprecipitation (1:10-1:500), Western Blot (1:100), Immunohistochemis... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: PA3-16786 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
