AP2 alpha Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA5105277 100 µL 550,00 Add

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Product Description

TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Category Antibody
Supplier ThermoFisher
Application ChIP, EL, ICC, IHC, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen A synthesized peptide derived from human AP 2, corresponding to a region within C-terminal amino acids.
Host Rb
Genebank TFAP2A
Isotype IgG
Crossreactivity Hu, Ms, Rt
Clonality Pab
Format Liquid; PBS; pH 7.4, with 50% glycerol and 0.02% sodium azide
Concentration 1 mg/mL
Working Dilution Immunocytochemistry (1:100-1:500), ChIP Assay (Assay-dependent), ELISA (Assay-dependent), Immunoh...
Purity Affinity chromatography
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA5-105277
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Wet Ice
Material Safety Data Sheet Download PDF