CaV1.2 Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA5109298 100 µL 498,00 Add

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Product Description

Positive Control: SKOV-3, rat brain tissue, human kidney tissue, human uterus tissue, mouse heart tissue. CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.

Category Antibody
Supplier ThermoFisher
Application DB, FC, ICC, IHC
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Synthetic peptide within mouse CACNA1C aa 802-851
Host Rb
Genebank CACNA1C
Isotype IgG
Crossreactivity Hu, Ms
Clonality Pab
Format Liquid; PBS; pH 7.4, with 0.2% BSA, 50% glycerol and 0.05% sodium azide
Concentration 1 mg/mL
Working Dilution Flow Cytometry (1:50-1:100), Immunohistochemistry (Paraffin) (1:50-1:200), Dot Blot (1:500-1:1,00...
Purity Affinity chromatography
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA5-109298
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF