H2BK12ac Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA5109814 | 100 µL | 552,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Sequence of this protein is as follows: APKKG Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthetic acetylated peptide around K12 of human Histone H2B (NP_003519.1). |
| Host | Rb |
| Genebank | H2B |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7.3, with 50% glycerol and 0.01% thimerosal |
| Concentration | 1.51 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:50-1:200), Immunocytochemistry (1:50-1:200), Western Blot (1:5... |
| Purity | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-109814 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
