UHRF1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA5116105 | 100 µL | 550,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthesized peptide derived from human UHRF1, corresponding to a region within N-terminal amino acids. |
| Host | Rb |
| Genebank | UHRF1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunoprecipitation (1:20-1:50), Western Blot (1:500-1:2,000), ChIP Assay (1:20-1:50), Immunocyto... |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-116105 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
