MMP13 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA5121879 | 20 µL | 174,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein Matrix Metalloproteinase 13. The antigen corresponds to amino acid range 70-245 of the target protein. |
| Host | Gp |
| Genebank | MMP13 |
| Isotype | IgG |
| Crossreactivity | Rb |
| Clonality | Pab |
| Format | Liquid; PBS; , with 50% glycerol and 0.05% ProClin 300 |
| Concentration | 0.93 mg/mL |
| Working Dilution | Immunocytochemistry (5-50 µg/mL), Western Blot (0.5-5 µg/mL), Immunohistochemistry (Paraffin) (5-... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: PA5-121879 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
