H3K9acK14ac Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA516194 | 100 µL | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other acetylated histones. Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Synthetic peptide corresponding to the amino terminus of histone H3 acetylated on lysines 9 and 14 |
Host | Rb |
Genebank | H3C1 |
Isotype | IgG |
Crossreactivity | Hu, Ms, Primate, Rt, Yeast |
Clonality | Pab |
Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and no preservative |
Concentration | 309 µg/mL |
Working Dilution | ChIP Assay (1:50), Western Blot (1:1,000), Immunoprecipitation (1:50), Immunohistochemistry (Para... |
Purity | Antigen affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | -20°C |
Disclaimer | Alternative CatNo: PA5-16194 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |