H4K20me1 Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA517027 100 µL 540,00 Add

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Product Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with mono-, di- or tri-methylated histone H3 at Lys4, Lys9, Lys27 or Lys36. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Category Antibody
Supplier ThermoFisher
Application ICC, WB
Regulatory Status RUO
Immunogen Synthetic peptide corresponding to the amino terminus of histone H4 in which Lys20 is mono-methylated
Host Rb
Genebank H4-16
Isotype IgG
Crossreactivity Bo, C.elegans, Drosophila, Ho, Hu, Ms, Primate, Pg, Rt, Xenopus, Zebrafish
Clonality Pab
Format Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and no preservative
Working Dilution Western Blot (1:1,000), Immunocytochemistry (1:250), Peptide array (1:2,000)
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions -20°C
Disclaimer Alternative CatNo: PA5-17027
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF