Caveolin 1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA517447 | 100 µL | 660,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with caveolin-2 or -3. Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide corresponding to residues surrounding Glu20 of human caveolin-1 |
| Host | Rb |
| Genebank | CAV1 |
| Isotype | IgG |
| Crossreactivity | Bo, Ck, Hm, Hu, Ms, Pg, Rt, Zebrafish |
| Clonality | Pab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and no preservative |
| Concentration | 33 µg/mL |
| Working Dilution | Immunoprecipitation (1:50), Western Blot (1:1,000), Immunohistochemistry (Paraffin) (1:250), Flow... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-17447 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
