Phospho-VASP (Ser157) Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA517768 | 100 µL | 674,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer157 of human VASP |
| Host | Rb |
| Genebank | VASP |
| Isotype | IgG |
| Crossreactivity | Gp, Hu, Ms, Primate, Rt |
| Clonality | Pab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and no preservative |
| Working Dilution | Western Blot (1:1,000) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-17768 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
