Phospho-NFkB p65 (Ser536) Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA517782 | 100 µL | 676,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the p50 subunit or other related proteins. Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer536 of human NF-kappaB p65 |
| Host | Rb |
| Genebank | RELA |
| Isotype | IgG |
| Crossreactivity | Dg, Hu, Ms, Primate, Pg, Rt |
| Clonality | Pab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and no preservative |
| Working Dilution | Western Blot (1:1,000) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-17782 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
