Histone H4 Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA517822 100 µL 606,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other histones. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Category Antibody
Supplier ThermoFisher
Application WB
Regulatory Status RUO
Immunogen Synthetic peptide corresponding to the amino-terminal sequence of human histone H4
Host Rb
Genebank H4-16
Isotype IgG
Crossreactivity Drosophila, Hu, Ms, Primate, Rt, Yeast, Zebrafish
Clonality Pab
Format Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and no preservative
Working Dilution Western Blot (1:1,000)
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions -20°C
Disclaimer Alternative CatNo: PA5-17822
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF