Ku80 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA518498 | 100 µg | 608,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide sequence (SLAKKDEKTDTLED) corresponding to the internal amino acids of XRCC5 |
| Host | Gt |
| Genebank | XRCC5 |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Liquid; TBS; pH 7.3, with 0.5% BSA and 0.02% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | ChIP Assay (2.5 µg/10^6 cells), Western Blot (0.1-0.5 µg/mL), Immunohistochemistry (5 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA5-18498 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
