HIF-2 alpha Polyclonal Antibody, DyLight™ 488
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA522695 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: hypoxic lysates. HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC, ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | A peptide derived from the C-terminus of mouse/human HIF-2 alpha protein. |
| Host | Rb |
| Genebank | EPAS1 |
| Isotype | IgG |
| Crossreactivity | Fish, Hm, Hu, Ms, Primate, Sh, Rb, Rt, Reptile |
| Clonality | Pab |
| Format | Liquid; 50mM sodium borate; , with no preservative |
| Concentration | 2 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:100), Western Blot (1:200-1:1,000), Immunohistochemistry (Froz... |
| Purity | Antigen affinity chromatography |
| Conjugation | DY 488 |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: PA5-22695 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
