BMI-1 Polyclonal Antibody, DyLight™ 550
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA522848 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: human and mouse skeletal muscle. Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Immunogen | A synthetic peptide made to an internal region (within residues 1-100) of the human Bmi1 protein. |
| Host | Rb |
| Genebank | BMI1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms |
| Clonality | Pab |
| Format | Liquid; 50mM sodium borate; , with no preservative |
| Concentration | 1.09 mg/mL |
| Working Dilution | Western Blot (0.5-2 µg/mL), Immunocytochemistry (Assay-Dependent) |
| Purity | Antigen affinity chromatography |
| Conjugation | DY 550 |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: PA5-22848 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
