Histone H3.3 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA523288 | 100 µg | 608,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide (119 TIMPKDIQLARRIRGERA 136) of Histone H3.3 protein. |
| Host | Rb |
| Genebank | H3-3A |
| Isotype | IgG |
| Crossreactivity | Bo, Ck, Drosophila, Ho, Hu, Marsupial, Ms, Zebrafish |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1.0 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (5-10 µg/mL), Western Blot (0.25-0.5 µg/mL) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA5-23288 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
