Phospho-Paxillin (Tyr118) Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA523327 | 20 µg | 682,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide (111 VGEEEHV(Y)SFPNKQK 125) of Phospho-Paxillin pTyr118 protein. |
| Host | Rb |
| Genebank | PXN |
| Isotype | IgG |
| Crossreactivity | Dg, Ck, Hu, Ms, Primate, Rb, Rt, Rhesus Monkey, Xenopus, Zebrafish |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.05% BSA and 0.05% sodium azide |
| Concentration | 0.2 mg/mL |
| Working Dilution | Western Blot (0.025-0.1 µg/mL), Immunocytochemistry (Assay-Dependent) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-23327 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
