Viperin Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA523508 | 100 µg | 738,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Viperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Portion of amino acids 165-215 of human viperin |
| Host | Rb |
| Genebank | RSAD2 |
| Isotype | IgG |
| Crossreactivity | Bo, Dg, Ck, Ho, Hm, Hu, Ms, Primate, Pg, Rb, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.05% BSA and 0.05% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (5 µg/mL), Western Blot (3-5 µg/mL) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-23508 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
