RAD51 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA527195 | 100 µL | 760,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: 293T, A431, HeLa, HepG2, Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (96%), Dog (98%), Pig (99%), Rabbit (97%), Chicken (95%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1 and 228 of Human Rad51 |
| Host | Rb |
| Genebank | RAD51 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt, Zebrafish |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.025% ProClin 300 |
| Concentration | 1.31 mg/mL |
| Working Dilution | Immunocytochemistry (1:100-1:1,000), Western Blot (1:500-1:3,000), Immunohistochemistry (Paraffin... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-27195 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
