Nrf2 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA527882 | 100 µL | 726,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: C8D30, 3xFlag-human NFE2L2-transfected 293T, MDA-MB-231 nuclear extract, MDA-MB-231 nuclear extract (30 µM tBHQ, 4hr), HepG2 (10 µM MG132 treatment for 15 hr). Predicted reactivity: Rhesus Monkey (99%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 108 and 413 of Human NRF2 |
| Host | Rb |
| Genebank | NFE2L2 |
| Isotype | IgG |
| Crossreactivity | Avian, Hu, Ms, Plant, Rt, Reptile, Zebrafish |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.025% ProClin 300 |
| Concentration | 1.27 mg/mL |
| Working Dilution | ChIP Assay (5 µg), Immunocytochemistry (1:100-1:1,000), Immunohistochemistry (Paraffin) (1:100-1:... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-27882 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
