Calcineurin A Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA529209 100 µL 658,00 Add

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Product Description

Recommended positive controls: Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, Molt-4, U87-MG, SK-N-SH, SK-N-AS, IMR32, JC, BCL-1, rat brain, human Calcineurin A-transfected 293T. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (90%), Xenopus laevis (98%), Dog (100%), Pig (99%), Rabbit (100%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.

Category Antibody
Supplier ThermoFisher
Application ChIP, ICC, WB
Regulatory Status RUO
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 264 of Human Calcineurin A
Host Rb
Genebank PPP3CA
Isotype IgG
Crossreactivity Amphibian, Hu, Ms, Rt, Rodent
Clonality Pab
Format Liquid; 0.1M tris glycine; pH 7, with 20% glycerol and 0.01% thimerosal
Concentration 0.98 mg/mL
Working Dilution ChIP Assay (Assay-Dependent), Western Blot (1:500-1:10,000), Immunocytochemistry (1:100-1:1,000)
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Disclaimer Alternative CatNo: PA5-29209
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF