TET3 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA531860 | 100 µL | 658,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: Flag-human TET3 transfected 293T. Predicted reactivity: Mouse (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1456 and 1660 of Human TET3 |
| Host | Rb |
| Genebank | TET3 |
| Isotype | IgG |
| Crossreactivity | Bo, Hu, Ms, Xenopus |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.025% ProClin 300 |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:100-1:1,000), Immunoprecipitation (1:500-1:1,000), Western Blot (1:1,000-1... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA5-31860 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
