GPR12 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA532793 | 50 µg | 678,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Opossum (100%); Bat, Elephant, Rabbit (94%); Turkey, Chicken (88%); Platypus, Xenopus (81%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic 16 amino acid peptide from 1st extracellular domain of human GPR12 / GPCR12. |
| Host | Rb |
| Genebank | GPR12 |
| Isotype | IgG |
| Crossreactivity | Dg, Ho, Hm, Hu, Monkey, Ms, Pg, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 0.8 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (10 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-32793 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
