HTR7 Polyclonal Antibody

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Product Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Dog, Hamster, Panda, Horse, Pig, Guinea pig (100%); Opossum (90%); Elephant (85%); Pufferfish, Zebrafish (80%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. 5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa. 5-HT7 Receptor has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel. An EST has been isolated from a testis library.