PDE1C Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA532969 50 µg 678,00 Add

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Product Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit (100%); Opossum (88%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).

Category Antibody
Supplier ThermoFisher
Application IHC
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Synthetic 16 amino acid peptide from C-terminus of human PDE1C.
Host Rb
Genebank PDE1C
Isotype IgG
Crossreactivity Bo, Ho, Hm, Hu, Monkey, Ms, Rb, Rt
Clonality Pab
Format Liquid; PBS; , with 0.1% sodium azide
Concentration 0.21 mg/mL
Working Dilution Immunohistochemistry (Paraffin) (5 µg/mL)
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA5-32969
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF