FZD7 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA533559 | 50 µg | 738,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human FZD7 / Frizzled 7. |
| Host | Rb |
| Genebank | FZD7 |
| Isotype | IgG |
| Crossreactivity | Bo, Hm, Hu, Monkey, Ms, Pg, Rb, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (5-10 µg/mL), Immunocytochemistry (1:100), Western Blot (1:1,000) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-33559 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
