RGR Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA534155 | 50 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Horse, Xenopus (100%) Bovine (94%). This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC |
| Regulatory Status | RUO |
| Immunogen | Synthetic 16 amino acid peptide from 2nd extracellular domain of human RGR. |
| Host | Rb |
| Genebank | RGR |
| Isotype | IgG |
| Crossreactivity | Ho, Hu, Xenopus |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 0.6 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (9-17 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
| Disclaimer | Alternative CatNo: PA5-34155 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
