TAOK1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA534250 | 50 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
TAOK1 is a serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascase, DNA damage response, and regulations of cytoskeleton stability. It phosphorylates MAP2K3, MAP2K6, and MARK2. TAOK1 acts as an activator of the p38/MAPK cascade by mediating phosphorylation and subsequent activation of the upsteam MAP2K3 and MAP2K6 kinases. It is involved in G-protein couples receptor signaling to p38/MAPK14. In response to DNA damage, TAOK1, is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade by phosphorylaton of MAP2K3 and MAP2K6. In addition, it acts as a regulator of cytoskeleton stability and a regulator of apoptosis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC |
| Regulatory Status | RUO |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human TAOK1. |
| Host | Rb |
| Genebank | TAOK1 |
| Isotype | IgG |
| Crossreactivity | Bo, Dg, Ho, Hm, Hu, Monkey, Ms, Pg, Rt, Xenopus |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (4.4 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
| Disclaimer | Alternative CatNo: PA5-34250 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
