Ku80 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA534758 | 100 µL | 676,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recommended positive controls: 293T, A431, HepG2, A375, Neuro2A, PC-12, Rat2. Predicted reactivity: Rhesus Monkey (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 315 and 593 of Ku80 (Uniprot ID#P13010) |
| Host | Rb |
| Genebank | XRCC5 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Primate, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 1% BSA, 20% glycerol and 0.025% ProClin 300 |
| Concentration | 0.41 mg/mL |
| Working Dilution | Western Blot (1:500-1:3,000), Immunoprecipitation (1:100-1:500), Immunocytochemistry (1:100-1:1,0... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-34758 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
