H4ac pan-acetyl (K5,K8,K12) Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA540083 | 50 µg | 672,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, ICC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | KLH-conjugated synthetic peptide corresponding to human the region of histone H4 containing the acetylated lysines 5, 8 and 12 (H4K5,8,12ac). |
| Host | Rb |
| Genebank | H4-16 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7.4, with 0.05% ProClin 300, 0.05% sodium azide |
| Concentration | 0.76 mg/mL |
| Working Dilution | ChIP Assay (1.5 µg/1x10^6 cells), ChIP-Sequencing (Assay-dependent), Peptide array (1:2,000), Wes... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-40083 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
