CD49a Polyclonal Antibody, APC
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA546899 | 100 Tests | 552,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Integrin alpha 2, rhIntegrin alpha 11, recombinant mouse (rm) Integrin alpha 2, and rmIntegrin alpha 11 is observed. Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | CHO-derived recombinant human Integrin alpha 1/CD49a Phe29-Pro1141 |
Host | Sh |
Genebank | ITGA1 |
Isotype | IgG |
Crossreactivity | Hu |
Clonality | Pab |
Format | Liquid; Buffered saline solution; , with BSA and 0.09% sodium azide |
Working Dilution | Flow Cytometry (10 µL per million cells) |
Purity | Antigen affinity chromatography |
Conjugation | APC |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: PA5-46899 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |