CXCL1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA546932 | 100 µg | 664,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In direct ELISAs, less than 50% cross-reactivity with recombinant human (rh) GRO beta and rhGRO gamma is observed, less than 25% cross-reactivity with recombinant mouse (rm) MIP-2 is observed, and less than 15% cross-reactivity with recombinant rat (rr) CINC-1, rrCINC-2 alpha, rrCINC-2 beta, rmKC, and rhIL-8 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | N, WB |
| Regulatory Status | RUO |
| Immunogen | E. coli-derived recombinant human CXCL1/GRO alpha/KC/CINC-1 Ala35-Asn107 |
| Host | Gt |
| Genebank | CXCL1 |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
| Concentration | 0.2 mg/mL |
| Working Dilution | Neutralization (0.03-0.15 µg/mL), Western Blot (0.1 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA5-46932 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
