NeuroD1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA547381 | 100 µg | 604,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Approximately 5% cross-reactivity with recombinant human NeuroD2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, WB |
| Regulatory Status | RUO |
| Immunogen | E. coli-derived recombinant human NeuroD1 Ser154-Asp356 |
| Host | Gt |
| Genebank | NEUROD1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms |
| Clonality | Pab |
| Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
| Concentration | 0.2 mg/mL |
| Working Dilution | Immunocytochemistry (5-15 µg/mL), Western Blot (0.1 µg/mL), ChIP Assay (2.5 µg/10^6 cells) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA5-47381 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
