AMHR2 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA547656 | 100 µg | 582,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant rat MIS RII is observed, and less than 1% cross-reactivity with recombinant human TGF-beta RI, RII, RIII, and RIIB is observed. Reconstitute at 0.2 mg/mL in sterile PBS. The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IHC, N, WB |
| Regulatory Status | RUO |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human MIS RII Pro18-Ser144 |
| Host | Sh |
| Genebank | AMHR2 |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
| Concentration | 0.2 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (5-15 µg/mL), Western Blot (0.1 µg/mL), Neutralization (Assay-Dep... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA5-47656 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
