IL-18 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA547803 | 100 µg | 540,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In direct ELISAs, approximately 50% cross-reactivity with recombinant canine IL-18, approximately 30% cross-reactivity with recombinant porcine IL-18, approximately 20% cross-reactivity with recombinant human IL-18 and recombinant rat IL-18, and less than 10% cross-reactivity with recombinant mouse IL-18 and recombinant rhesus macaque IL-18 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | N, WB |
| Regulatory Status | RUO |
| Immunogen | E. coli-derived recombinant feline IL-18/IL-1F4 Tyr36-Asn192 |
| Host | Sh |
| Genebank | IL18 |
| Isotype | IgG |
| Crossreactivity | Ca |
| Clonality | Pab |
| Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
| Concentration | 0.2 mg/mL |
| Working Dilution | Neutralization (2-12 µg/mL), Western Blot (0.1 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA5-47803 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
