PCDH15 Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA547865 100 µg 738,00 Add

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Product Description

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Protocadherin-1, rhProtocadherin-8, and rhProtocadherin-10 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL. PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

Category Antibody
Supplier ThermoFisher
Application ICC, IHC, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen CHO-derived recombinant human Protocadherin-15 Gln27-Ala1376
Host Sh
Genebank PCDH15
Isotype IgG
Crossreactivity Hu
Clonality Pab
Format Lyophilized; PBS; , with 5% trehalose and No Preservative
Concentration 0.2 mg/mL
Working Dilution Immunocytochemistry (5-15 µg/mL), Western Blot (2 µg/mL), Immunohistochemistry (Paraffin) (5-15 µ...
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA5-47865
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF