ABCG1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA572939 | 100 µL | 682,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthetic peptide made to an internal region of human ABCG1 (between residues 300-400). [UniProt# P45844] |
| Host | Rb |
| Genebank | ABCG1 |
| Isotype | IgG |
| Crossreactivity | Hm, Hu, Ms, Primate, Rb, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (1:500), Immunohistochemistry (Paraffin) (1:100-1:400), In vitro Assay (Assay-Depend... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: PA5-72939 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |