ATF3 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA572945 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | A synthetic peptide corresponding to a region of human ATF3 (within residues 100-150). [UniProt# P18847] |
| Host | Rb |
| Genebank | ATF3 |
| Isotype | IgG |
| Crossreactivity | Hu, Ma, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 30% glycerol and 0.1% sodium azide |
| Concentration | 1.27 mg/mL |
| Working Dilution | ELISA (1:100-1:2000), Western Blot (1:200), Immunohistochemistry (Paraffin) (5 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA5-72945 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
