PGC1 alpha Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA572948 | 100 µL | 608,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PGC1 alpha is a transcriptional coactivator that regulates the genes involved in energy metabolism. It interacts with PPARgamma, which permits it's interaction with multiple transcription factors. PGC-1 Alpha can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. It may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide made to an internal portion of the human PGC-1 alpha protein (within residues 400-550). [Swiss-Prot# Q9UBK2]. |
| Host | Rb |
| Genebank | PPARGC1A |
| Isotype | IgG |
| Crossreactivity | Hm, Hu, Ms, Rt, Rodent |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.02% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:1,000), Immunoprecipitation (Assay-Dependent), Western Blot (1-2 µg/mL), I... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA5-72948 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
