Amyloid Fibrils Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA577843 | 100 µL | 746,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Specificity: recognizes generic epitopes common to many amyloid fibrils and fibrillar oligomers, but not prefibrilllar oligomers or natively folded proteins. Expected to detect Mouse and Rat based on species homology. Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid-beta peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of alpha-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | DB, EL, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Fibrils prepared from human amyloid beta 42 peptide |
| Host | Rb |
| Genebank | APP |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7.4, with 50% glycerol and 0.09% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Immunocytochemistry (Assay-Dependent), ELISA (Assay-Dependent), Dot Blot (1:1,000), Immunoprecipi... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-77843 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
