NeuroD1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA578075 | 100 µL | 730,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Positive Control: IMR32, IMR32 nuclear extract Predicted Reactivity: Mouse (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse NeuroD1. The exact sequence is proprietary. |
| Host | Rb |
| Genebank | NEUROD1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 1% BSA, 20% glycerol and 0.025% ProClin 300 |
| Concentration | 0.47 mg/mL |
| Working Dilution | ChIP Assay (2.5 µg/10^6 cells), Immunocytochemistry (5 µg/mL), Immunohistochemistry (Frozen) (1:1... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-78075 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |