NeuroD1 Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA578075 100 µL 730,00 Add

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Product Description

Positive Control: IMR32, IMR32 nuclear extract Predicted Reactivity: Mouse (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

Category Antibody
Supplier ThermoFisher
Application ChIP, ICC, IHC, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse NeuroD1. The exact sequence is proprietary.
Host Rb
Genebank NEUROD1
Isotype IgG
Crossreactivity Hu, Ms, Rt
Clonality Pab
Format Liquid; PBS; pH 7, with 1% BSA, 20% glycerol and 0.025% ProClin 300
Concentration 0.47 mg/mL
Working Dilution ChIP Assay (2.5 µg/10^6 cells), Immunocytochemistry (5 µg/mL), Immunohistochemistry (Frozen) (1:1...
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA5-78075
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Wet Ice
Material Safety Data Sheet Download PDF