S100B Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA578161 | 100 µL | 654,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Positive Control: V5-human S100B-transfected 293T, A375, mouse brain, rat brain Predicted Reactivity: Rabbit (100%), Chicken (84%), Rhesus Monkey (98%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Full length human S100 beta Recombinant protein. |
| Host | Rb |
| Genebank | S100B |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt, Rodent |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 1% BSA, 20% glycerol and 0.025% ProClin 300 |
| Concentration | 0.09 mg/mL |
| Working Dilution | Immunohistochemistry (Frozen) (1:100-1:1,000), Western Blot (1:500-1:3,000), Immunocytochemistry ... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA5-78161 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
