TCF7 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA578191 | 100 µL | 734,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Positive Control: HepG2, Jurkat Predicted Reactivity: Mouse (97%), Bovine (95%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human TCF7. The exact sequence is proprietary. |
| Host | Rb |
| Genebank | TCF7 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.01% thimerosal |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (1:500-1:3,000), Immunoprecipitation (1:100-1:500), ChIP Assay (2.5 µg/10^6 cells), ... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-78191 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
