HDAC1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA585093 | 100 µL | 682,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Keep as concentrated solution. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (80%), Bovine (98%). Positive Control: 293T, A431, HeLa, HepG2, U87-MG, SK-N-SH, NIH3T3, Rat-2, E8.5 embryo. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HDAC1. |
| Host | Rb |
| Genebank | HDAC1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.01% thimerosal |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:100-1:1,000), Immunocytochemistry (1:100-1:1,000), Immunopreci... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-85093 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
