HIF-2 alpha Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA585190 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Keep as concentrated solution. Predicted reactivity: Mouse (97%), Rat (95%), Xenopus laevis (86%), Pig (99%), Chicken (94%), Bovine (98%). Positive Control: HepG2 (1% O2 treatment for 24hr), HT1080, 786-0, FADU. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. |
| Host | Rb |
| Genebank | EPAS1 |
| Isotype | IgG |
| Crossreactivity | Hu, Zebrafish |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.025% ProClin 300 |
| Concentration | 1 mg/mL |
| Working Dilution | ChIP Assay (2.5 µg/10^6 cells), Western Blot (1:500-1:3,000), Immunocytochemistry (1:100) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA5-85190 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
