5-Methylcytosine Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA585516 | 100 µL | 678,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Keep as concentrated solution. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | DB, IP |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | The immunogen used to generate this antibody corresponds to 5-MethylCytosine/ 5-mC |
| Host | Rb |
| Isotype | IgG |
| Crossreactivity | Chemical |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7, with 20% glycerol and 0.025% ProClin 300 |
| Concentration | 7.55 mg/mL |
| Working Dilution | Immunomicroscopy (Assay-dependent), Methylated DNA Immunoprecipitation (Assay-dependent), Dot Blo... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA5-85516 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
