Phospho-HEC1 (Ser55) Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA585846 100 µL 596,00 Add

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Product Description

Positive Control: HeLa, Blocking peptide, HeLa (100 ng/mL Nocodazole treatment for 24 hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.

Category Antibody
Supplier ThermoFisher
Application EL, ICC, IP, WB
Regulatory Status RUO
Immunogen Synthetic phosphopeptide corresponding to the amino acids around Ser 55 conjugated to KLH.
Host Rb
Genebank NDC80
Isotype IgG
Crossreactivity Hu, Ms, Rt, Rodent
Clonality Pab
Format Liquid; PBS; pH 7, with 1% BSA, 20% glycerol and 0.025% ProClin 300
Concentration 0.26 mg/mL
Working Dilution Western Blot (1:500-1:3,000), Immunocytochemistry (1:300), ELISA (Assay-dependent), Immunoprecipi...
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Disclaimer Alternative CatNo: PA5-85846
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF