INHA Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA595909 | 100 µL | 604,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Immunogen sequence: CQGLELAREL VLAKVRALFL DALGPPAVTR EGGDPGVRRL PRRHALGGFT HRGSEPEEEE DVSQAILFPA TDASCEDKSA ARGLAQEAEE GLFRYMFRPS QHTRSRQVTS AQLWFHTGLD RQGTAASNSS EPLLGLLALS PGGPVAVPMS LGHAPPHWAV LHLATSALSL LTHPVLVLLL RCPLCTCSAR PEATPFLVAH TRTRPPSGGE RARRSTPLMS WPWSPSALRL LQRPPEEPAA HANCHRVALN ISFQELGWER WIVYPPSFIF HYCHGGCGLH IPPNLSLPVP GAPPTPAQPY SLLPGAQPCC AALPGTMRPL HVRTTSDGGY SFKYETVPNL LTQHCACI; Positive Samples: Rat testis The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Category | Antibody |
Supplier | ThermoFisher |
Application | IHC, WB |
Regulatory Status | RUO |
Immunogen | A synthetic peptide corresponding to amino acids 200-300 of human INHA. |
Host | Rb |
Genebank | INHA |
Isotype | IgG |
Crossreactivity | Hu, Ms, Rt |
Clonality | Pab |
Format | Liquid; PBS; pH 7.3, with 50% glycerol and 0.05% ProClin 300 |
Concentration | 1.69 mg/mL |
Working Dilution | Immunohistochemistry (Paraffin) (1:50-1:200), Western Blot (1:500-1:2,000) |
Purity | Affinity Chromatography |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: PA5-95909 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |